The upcoming International Conference on Cardiology and Cardiovascular Science, happening March 26-28, 2026 in Singapore and Online, will feature a remarkable keynote by Dr. Lu Cai, a leading researcher from the University of Louisville School of Medicine, USA.
Dr.
Cai will discuss the complex mechanisms behind diabetic
cardiomyopathy (DCM) and the critical role of metal-mediated cell death
in disease progression. His research highlights cutting-edge discoveries that
could transform future therapies for diabetic heart disease.
Highlights from the Keynote Presentation:
·
Cardiac inflammation and myocyte
death are key drivers of DCM.
·
Identification of diverse types of cell death, including apoptosis,
necroptosis, pyroptosis, autophagy, ferroptosis, and cuproptosis.
·
Ferroptosis
emerges as a major mechanism in DCM, triggered by advanced
glycation end-products (AGEs).
·
Engineered cardiac tissue studies
reveal ferroptosis through changes in Ptgs2, lipid peroxides, ferritin, and
SLC7A11.
·
Protective interventions with ferrostatin-1, deferoxamine, and
liproxstatin-1 successfully prevent cardiac dysfunction.
·
Sulforaphane,
via AMPK-dependent
NRF2 activation, inhibits ferroptosis and offers cardiac
protection.
·
Investigating the influence of metals like copper, zinc,
and cadmium on cardiomyocyte health and DCM progression.
·
Opens pathways for next-generation therapies targeting metal-dependent cell death
in diabetes-related heart disease.
Dr.
Cai’s research continues to illuminate the intricate connections between metals, cell
death, and heart health, paving the way for innovative
treatments that could significantly reduce diabetic heart complications.
Event Name: International
Conference on Cardiology and Cardiovascular Science
📅 Event Dates:
March 26-28, 2026
📍 Venue:
Singapore & Online
🔗 Register Now:
https://cardiology.miconferences.com/register
✉️ Contact:
cardiology@mathewsconference.com
📞 Phone:
+1 (312) 462-4448
💬 WhatsApp:
+1 (424) 377 0967
#DiabeticCardiomyopathy #FerroptosisResearch
#MetalMediatedCellDeath #CardiologyInnovation #HeartDiseasePrevention
#DiabetesComplications #SulforaphaneTherapy #MedicalResearch
#CardiologyConference2026 #SingaporeEvents
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