Understanding how metabolic markers interact with gut microbiota is becoming increasingly vital in predicting cardiovascular disease risk. At the upcoming International Conference on Cardiology and Cardiovascular Science (March 26–28, 2026), Prof. Gulshara Abildinova from Kazakhstan will present an in-depth study exploring the relationship between the Triglyceride-Glucose (TG/G) index and the species composition of the gut microbiome in patients with insulin resistance.
Her research highlights important microbial and clinical signatures that may influence cardiovascular outcomes and metabolic health.
Study Highlights
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189 Patients Investigated
Participants (mean age ~49 years) included men and women diagnosed with insulin resistance, allowing a diverse metabolic profile. -
Advanced DNA Sequencing Applied
Gut microbiome composition was analyzed using the Ion Gene Studio S5 Plus semiconductor sequencer, targeting 16S rRNA gene segments. -
Significant Clinical Correlations Found
Elevated TG/G index values (>1.7 mmol/L) were linked to higher ESR, hemoglobin, leukocyte counts, platelets, and LDL cholesterol (p < 0.001). -
Cardiac Structure & Function Affected
• Heart failure observed in 16% of cases
• Diastolic dysfunction identified in 91 patients
• Carotid intima-media thickening and plaques strongly associated with TG/G levels -
Distinctive Microbial Patterns Identified
High TG/G values correlated with greater abundance of:
– Bacteroidaceae
– Prevotella copri
– Enterobacter asburiae
– Firmicutes and Proteobacteria -
Pro-Inflammatory Microbial Shifts Noted
Increased Proteobacteria suggests a link between microbial imbalance, insulin resistance, and inflammation-driven cardiovascular complications. -
Holistic Assessment Recommended
The study supports integrating microbiome analysis with cardiometabolic markers to improve early detection and risk prediction.
About Prof. Gulshara Abildinova
Prof. Abildinova is a highly respected geneticist and professor with:
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36 years of academic and scientific experience
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Over 200 published research papers and 65 post-doctoral publications
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7 patents, 5 methodological guidelines, and 4 monographs
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Leadership as head of the Personalized Genomic Diagnostics Laboratory at the Presidential Administration Hospital of Kazakhstan
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Major contributions to national programs for prenatal and newborn genetic screening
Her work has played a pivotal role in advancing medical genetics and public health initiatives across Kazakhstan.
Conference Information
Event: International Conference on Cardiology and Cardiovascular Science
Dates: March 26–28, 2026
Format: Hybrid (Singapore + Online)
Email: cardiology@mathewsconference.com
Phone: +1 (312) 462-4448
WhatsApp: +1 (424) 377 0967
🔗 Event Website: https://cardiology.miconferences.com/
🔗 Abstract Submission: https://cardiology.miconferences.com/abstract-submission
🔗 Registration: https://cardiology.miconferences.com/register
🔗 Follow on X: https://x.com/CardioEvent_CVS
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