At the upcoming International Conference on Cardiology and Cardiovascular Science 2026, Professor Terry McCormack from Hull York Medical School, United Kingdom, will deliver an eye-opening keynote on why many patients with hypertension discontinue their prescribed medications — specifically mineralocorticoid receptor antagonists (MRAs).
His
presentation, titled “High
Rates of Mineralocorticoid Receptor Antagonist Discontinuation in Patients with
Hypertension: Insights from the Enlighten Study,”
explores global treatment patterns and the pressing need for improved adherence
strategies.
π
Key Insights from the Enlighten Study
✅ Study Overview:
The study examined MRA discontinuation rates among patients with
hypertension (HTN) across multiple countries — the United
States, United Kingdom, and Spain — between 2018 and 2023.
✅ Data Sources:
Used large, trusted databases such as TelotrΓ³n (Spain), IQVIA EMR (US),
and CPRD
(UK), providing a real-world perspective on medication
adherence.
✅ Study Population:
Over 15,000
patients included, ensuring strong comparative results.
✅ Key Findings by Country:
·
πΊπΈ US:
71% discontinued within 12 months; 85% within 24 months
·
πͺπΈ Spain:
63% at 12 months; 77% at 24 months
·
π¬π§ UK:
41% at 12 months; 58% at 24 months
✅ Critical Takeaway:
Despite proven cardiovascular benefits, most patients stopped MRAs within one to two years,
revealing major challenges in medication persistence.
✅ Clinical Relevance:
Professor McCormack highlighted that sustaining therapy is crucial for preventing heart
complications and managing long-term hypertension outcomes.
✅ Notable Observation:
Patients in the UK demonstrated better adherence than those in the US and Spain,
suggesting systemic and clinical practice differences worth further
exploration.
π¨⚕️ About Professor Terry McCormack
·
General Practitioner &
Honorary Professor of Primary Care Cardiovascular Medicine,
Hull York Medical School
·
Immediate Past President,
British and Irish Hypertension Society
·
Contributed to NICE and AAGBI/BHS clinical guidelines
·
Editor,
British Journal of Cardiology
·
Fellow,
European Society of Cardiology
His decades-long contribution to cardiovascular research and clinical guidelines
continues to shape hypertension management worldwide.
π
Join the Global Cardiology Dialogue
Don’t
miss this opportunity to connect with world-leading experts in cardiovascular
research!
Event
Name: International
Conference on Cardiology and Cardiovascular Science
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cardiology@mathewsconference.com
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+1 (312) 462-4448
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