Evidence Update on Colchicine Dosing for Cardiovascular and Stroke Protection
Presenter: Reem Alsheikh
Affiliation: King
Saud University for Health Sciences, Saudi Arabia
Presentation Format:
Oral Presentation (In-Person)
Tittle: Low dose vs. higher doses of colchicine for secondary prevention of
ischemic stroke and cardiovascular disease. an updated grouped meta-analysis of
landmark trials
Dr. Reem Alsheikh
will present an updated grouped meta-analysis of landmark trials comparing
low-dose versus higher-dose colchicine for secondary prevention of ischemic
stroke and cardiovascular disease. The presentation highlights evidence
supporting low-dose colchicine as a more effective and well-tolerated adjunct
therapy for reducing recurrent cardiovascular and cerebrovascular events.
🔬 Presentation Overview
Study Focus
A systematic
review and updated grouped meta-analysis comparing low-dose versus higher-dose
colchicine for secondary prevention of ischemic stroke and cardiovascular
events.
Key Findings
Low-dose
colchicine (≤0.5 mg/day) significantly reduced ischemic stroke risk, major
adverse cardiovascular events, and myocardial infarction compared with placebo.
Dose–Response Insight
Greater clinical
benefit was observed with low-dose, once-daily colchicine regimens compared
with higher doses.
Patient Subgroup Benefit
Younger patients
(<65 years) demonstrated the most pronounced reduction in ischemic stroke
risk.
Safety and Mortality
Colchicine showed
a neutral effect on all-cause mortality, supporting a favorable safety profile
at low doses.
Clinical Implications
Findings support
low-dose colchicine as an effective adjunct therapy for secondary prevention of
ischemic stroke and cardiovascular disease in selected patients.
Future Directions
Further
large-scale and long-term studies are needed to refine patient selection and
inform guideline-based dosing strategies.
👩⚕️ About the Speaker
Dr. Reem Mohammed
Alsheikh, Assistant Professor in King Saud University for Health Science,
Consultant Family Medicine in National Guard Primary Health care center, kn
Jeddah, Saudi Arabia. I have a clinical experience for more than twenty years,
trainer for residency program for sixteen years, I am currently Residency
Program Director of Family Medicine program for Western Region, National Guard.
📅 Conference Details
Event: International Conference on Cardiology and
Cardiovascular ScienceDates: March 26–28, 2026
Venue: Singapore & Online
Website: https://cardiology.miconferences.com/
#SecondaryPrevention#Colchicine#SystematicReview#Cardiology#Cardiology2026 #CVS2026 #CardiologyConference#Mathewsconference
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