The cause and mechanism of atherosclerosis requires revision

 A New Perspective on Atherosclerosis

Presenter: Ermoshkin Vladimir Ivanovich
Affiliation: RosNOU, Russian Federation
Presentation Format: Oral Presentation (Virtual)

Tittle: The cause and mechanism of atherosclerosis requires revision

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🔬 Presentation Overview

🧩 Background Perspective

Understanding the true cause of atherosclerosis remains a subject of ongoing debate. This work presents a critical re-examination of atherosclerosis by integrating human observations, experimental findings, and published scientific evidence.

🔍 Central Proposition

This study proposes that the primary initiating factor of atherosclerosis is the periodic leakage of arterial blood into the venous system, rather than lipid accumulation alone.

⚙️ Vascular Mechanical Changes

Repeated arterial blood leakage leads to a reduction in tissue pressure within the stretched muscular layer of arteries. This mechanical alteration plays a key role in initiating vascular wall damage.

🧬 Endothelial Disruption

As tissue pressure decreases, endothelial dysfunction develops, creating microscopic crevices within the arterial lining.

🧪 Lipoprotein Entry

These endothelial gaps allow low-density lipoproteins (LDL) to be drawn into the vessel wall, marking the beginning of lipid infiltration and structural injury.

🩺 Disease Progression

As vascular injury advances, atherosclerotic plaques may subsequently develop in other arterial regions beyond bifurcation zones.

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👩‍⚕️ About the Speaker

Ermoshkin Vladimir Ivanovich was born on February 13, 1948. In 1978, he graduated from the Physics Department of Moscow State University. He worked as a physicist in several institutions. Then he worked at RosNOU as a research physicist. He published about 15 medical articles in Russian in 2015-2025. There are about 5 articles in English in the same years.

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📅 Conference Details

Event: International Conference on Cardiology and Cardiovascular Science
Dates: March 26–28, 2026
Venue: Singapore & Online
Website: https://cardiology.miconferences.com/

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